Who we are
Innovavector is a young-accomplished CDMO well established in the world of gene therapy, bringing experience and innovation in the production of adeno-associated viral vectors from bench to manufacturing.
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Young
Founded in 2020 as a spin-off of the Telethon Institute of Genetics and Medicine (TIGEM), Innovavector brings a dynamic team that leads a new and innovative vision in the development of gene therapies.
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Experienced
The company leverages the 20+ years of experience of TIGEM and Alberto Auricchio’s Vector Core team in developing, optimizing and manufacturing AAVs for gene therapy applications.
Our history
InnovaVector has been built on the expertise in AAV production, purification and characterization established at the Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, in particular within its AAV Vector Core.
Thanks to our cooperation with TIGEM, we count on a strong intellectual property, such as:
- Proprietary plasmids and cell bank for AAV manufacturing
- Wide range of AAV serotypes available
- Proprietary platforms for AAV manufacturing, with both adherent and suspension cell lines
Our mission
Our mission is to improve and optimize customers’ AAV production processes, accompanying them from molecule to clinical trial and maintaining the highest quality and process standards.
OUR TEAM
Leadership Team
Fabio Perini, MBA
Chief Operating Officer (COO)
Read the bio +Fabio has held the role of Chief Operating Officer at Innovavector since May 2024.
He joined InnovaVector in 2022, first as Chief Business Officer and bringing to the company the solid experience in advanced therapies gained at MolMed (now AGC Biologics), a pioneer company in gene therapy, as process developer and later as Business Developer.
He also served as Marketing Manager for Biologics at Eli Lilly.
Fabio holds a Master degree in molecular biology from the university of parma and a master in business administration at SDA Bocconi school of management.
Riccardo Palmisano, MD
Chief Executive Officer (CEO)
Read the bio +Graduate in Medicine and Surgery from the University of Parma, he received additional training in management and leadership.
Riccardo boasts a multi-year professional career in big corporations, covering general management and commercial strategy roles for important pharmaceutical multinationals. His background is also closely linked to the world of advanced therapies, having held top positions of key companies such as Genzyme and MolMed, of which he was CEO from 2015 to 2020 and led the acquisition of the company by the AGC inc.
Riccardo joined InnovaVector in October 2022, holding the role of Chief Executive Officer.
Mariangela Lubrano Lavadera
Head of Administration, Finance&Control (AFC)
Read the bio +Mariangela holds a Master degree in economics and business administration from the University of Naples, and gets certification as a certified public accountant and auditor accounts.
She brings more than 18 years of experience in the AFC area(Administration, Finance and Control), as an auditor(Pwc), Group Financial Controller and CFO in companies of medium/large size companies.
Mariangela currently holds the position of Head of Administration, Finance& Control in InnovaVector Srl.
Andrea Ferrante
Business Development Manager
Read the bio +Andrea holds a Master’s Degree in Molecular Biology from the University of Milan in 2014 and has been active in the field of advanced therapy since the beginning of his career. Before joining InnovaVector, he was involved in AGC biologics (formerly MolMed) leading the Upstream team for large-scale viral vector production and later gained experience as Sales Development Manager at Cytiva, managing projects and leading crucial negotiations with the largest pharmaceutical companies and refining and integrating commercial, scientific and technical skills.
Andrea has been part of InnovaVector as Business Development Manager since May 2024.
Chiara Piscopo
Quality Control Manager
Read the bio +Chiara held MSc degree in medical biotechnology at Università degli studi di Napoli Federico II in 2017 and has been active in advanced therapy field since 2016. She gained salient experience for several years in Reithera, at the beginning as R&D grade AAV Vectors development scientist and then as Quality Control specialist.
Chiara joined InnovaVector in October 2020 as Quality control senior scientist and from 2023 as Quality control manager.
Annagiusi Gargiulo, Ph.D
Project Manager and Qualified Person
Read the bio +Mariangela holds a Master degree in economics and business administration from the University of Naples, and gets certification as a certified public accountant and auditor accounts.
She brings more than 18 years of experience in the AFC area(Administration, Finance and Control), as an auditor(Pwc), Group Financial Controller and CFO in companies of medium/large size companies.
Mariangela currently holds the position of Head of Administration, Finance& Control in InnovaVector Srl.
Monica Doria
Discovery Research Manager
Read the bio +Monica Doria has extensive experience in the field of genetic research and extensive technical know-how in the production of viral vectors that has lasted for over twenty years. She currently works as research grade AAV production manager at InnovaVector since 2020.
Previously, from 2002 to 2020, she managed the AAV Vector Core Facility of TIGEM (Telethon Institute of Genetics and Medicine, Pozzuoli, Italy) and developed a production and purification process that allowed the production of thousands of batches of AAV vectors for use in preclinical studies. Previously, after graduating at Federico II University of Naples, she dedicated herself to scientific research studying molecular mechanisms of the action of hormones on neoplastic cells, at the Vanvitelli University of Naples.
Antonio Romano
Supply Chain Manager
Read the bio +Antonio held MSc degree in Pharmaceutical Biotechnology at Università degli studi di Siena and MBA at Bologna Business School.
Before joining InnovaVector in 2021, Antonio covered several positions into multinational companies. From Novartis Vaccines & Diagnostic and GlaxoSmithKline where he gained experiences in Supplier Quality, Aseptic Production and Direct Procurement to Philip Morris International where first in Bologna and then in London he had the chance to increase his know-how into the FCMG industry covering roles of increasing responsibility into the SupplyChain and IM&S Procurement.
Gael Mbele, PhD
Head of Process Development and Tech Transfer
Read the bio +Gael has extensive knowledge and experience in the field of the gene and cell therapy, particularly in the development and optimization of full processes (Upstream amd Downstream) for LV and AAV production/purification for clinical trial using adherent and suspension-serum free cell lines.
With a solid scientific career, he has played relevant roles in renowned biotech companies such as Theravectys and Yposkesi where he has managed and coordinated multidisciplinary research projects with international teams.
In 2021 Gael joined InnovaVector and currently he is Head of Process Development and Technology Transfer at InnovaVector.
Carlo Catalanotti
GMP Manufacturing Manager
Read the bio +Carlo is a chemical engineer with long experience in the field of production and quality assurance in manufacturing of AAV virus, injectable liquids (Vaccines) in Aseptic Operations, and of APIs for pharmaceutical and food applications produced by fermentation and/or synthetic pathway in CDMO organizations.
During his professional experience he has held several roles in multinational companies, mainly in the field of Quality & Sterility Assurance, Production Management and implementation of new products from the development to production on an industrial scale.
In 2023 Carlo joined InnovaVector leading the GMP manufacturing unit.
Rito Visciano
Engineering and Facility Manager
Read the bio +Rito graduated cum laude in Chemical Engineering at the “Federico II” University of Naples after completing his studies collaborating with Plasmon, Kraft-Heinz group, on the fermentation of engineered bacterial strains and then Rito joined UNILEVER within the Italian Global Research Center in Casalpusterlengo (LO) within the CTI team of Hard Suface Cleaners.
In 2011 Rito held firstly Process Engineer in bacterial area and then Reliability site engineer role for Glaxo, Smith & Kline at the Siena-Rosia site (formerly Novartis Vaccines & Diagnostics), gaining knowledge and responsibilities into the Engineering Dept as Reliability Eng Team Coordinator. During this experience he had the opportunity, among other activities, to participate in several AIFA, FDA and other Authorities Audits for the Engineering Department.
Before joining InnovaVector, Rito held a crucial role in Menarini Farmaceutici (IT) as Corporate Engineering Manager following the realization of a Green Field Pharmaceutical Site for vaccine production, coordinating the construction, commissioning and qualification activities.
Since 2020 Rito is part of the InnovaVector team as Engineering and Facility Manager, following the construction, start-up, commissioning and qualification activities of the new Gene Therapy facility in the city of Pozzuoli (NA).
Scientific and Technical Advisor team
Alberto Auricchio, MD
Scientific Director, Principal Investigator at TIGEM (Telethon Institute of Genetics and Medicine)
Read the bio +Alberto Auricchio, MD is Professor of Medical Genetics at the Department of Advanced Biomedicine, University in Naples “Federico II”, and Scientific Director of Telethon Institute of Genetics and Medicine (TIGEM) in Pozzuoli (NA), Italy. His research is focused on gene therapy of retinal and metabolic diseases using adeno-associated viral vectors. His group has contributed to the phase I/II clinical trial of Luxturna, the first approved gene therapy drug for an ocular disease, and to the development of gene therapy for mucopolysaccharidosis VI in an ongoing phase I/II trial.
He is also co-author of more than 150 peer-reviewed publications in international scientific journals and inventor of several international patents on the use of viral vectors for gene therapy. Prof. Auricchio is founder, shareholder and consultant of InnovaVector and AAVantgarde Bio, a spin-off interested in developing novel gene therapies for blindness. He is a member on the editorial boards of various journals and of the Executive Board of the European Society of Cell and Gene Therapy.
Dionigio Franchi, PhD
Quality and Regulatory Advisor member
Read the bio +Dionigio graduated in Chemistry from the University of Padua and has thirty years of experience in the pharmaceutical field where he held the role of Director of the PD division in GSK R&D. Dionigio also brings to the company a great knowledge of Quality assurance and regulatory affairs in the pharmaceutical field, also thanks to the consolidated experience in Operating under a variety of Quality Systems, such as Company Standard Operating Procedures; GLP and GMP compliant; GLP authorized testing facilities; Controlled drug substances authorization; API manufacturing GMP authorization; Drug Product Manufacturing License; Validated LIMS system and Preparing Chemistry Manufacturing Controls (CMC) sections of regulatory documents (IB, IMPD, IND, NDA, MAA) and addressing regulatory questions.
Marco Manoni, PhD
Technical and Facility Advisor Member
Read the bio +Gradiated in biological sciences, Marco has held several crucial and roles in the pharma and biotech context, as Director of Operations and Facility Planning & Design Director, as well as Safety Director in MolMed SpA, General Manager for more than 10 years at RSM SpA, an R&D company focused on development and production of intermediates and APIs; Responsible for the development and production of PRIMM, one of the first biotech companies in Italy and Site manager of RSM Vicchio SpA, (formerly Società Chimica del Mugello, Florence).
Currently Marco is bringing his experience in InnovaVector Srl as Senior Advisor.